P43322-B21 - HPE 16GB SR x8 DDR5-4800 Smart Memory Kit

HPE P43322-B21 — 16GB (1×16GB) DDR5-4800 Registered ECC Smart Memory (Gen11)

What it is

P43322-B21 is an HPE Smart Memory RDIMM for ProLiant Gen11 servers.
It’s a 16GB DDR5 Registered ECC module running at 4800 MT/s, built and qualified by HPE to match Gen11 platform requirements. Think “the standard 16GB DDR5 RDIMM you add to DL360/DL380 Gen11 and friends.”

Why buyers pick P43322-B21 (plain English)

• Certified Gen11 compatibility
  HPE Smart Memory is validated for ProLiant Gen11 systems, so you avoid BIOS/firmware drama.

• Registered ECC reliability
  RDIMM + ECC is the server-safe choice for uptime and data integrity.

• Good building block size
  16GB sticks are a clean way to scale memory without jumping straight to high-cost DIMMs.

• Platform features unlocked
  Smart Memory enables proper performance profiles and health reporting on supported HPE servers.

60-second spec box (P43322-B21)

Capacity

• 16 GB

Module type

• DDR5 RDIMM (Registered DIMM)

Speed / standard

• DDR5-4800 (PC5-38400 class)

Rank / organization

• Single Rank (1R×8)

ECC / reliability

• ECC Registered (server-grade)

Voltage

• 1.1V

Pins / form factor

• 288-pin DIMM

Target platforms

• HPE ProLiant Gen11 and other HPE systems that specify DDR5-4800 RDIMM Smart Memory

Where it fits (and when to choose something else)

Perfect for:

• Expanding memory in Gen11 ProLiant servers

• Virtualization hosts, general compute, database/app tiers

• Standard enterprise RAM upgrades needing ECC RDIMMs

Choose something else if:

• Your server requires LRDIMM instead of RDIMM

• You need higher capacity per slot → 32/64/128GB DDR5 RDIMMs

• You’re on Gen10/Gen10+ (DDR4 platform) → use DDR4 Smart Memory instead

TL;DR

P43322-B21 is HPE’s 16GB DDR5-4800 ECC Registered Smart Memory RDIMM for Gen11 servers: a dependable, platform-qualified 16GB stick for scaling ProLiant Gen11 memory the clean way.